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apalutamide will lessen the level or impact of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a robust CYP2C19 inducer, with medications which are CYP2C19 substrates can result in reduced publicity to those prescription drugs.C: Use with warning if Positive aspects o